Fragmented Nuclear DNA is the Predominant Genetic Material in Human Hair Shafts
نویسندگان
چکیده
منابع مشابه
Hair Shafts
L. Rudnicka et al. (eds.), Atlas of Trichoscopy, DOI 10.1007/978-1-4471-4486-1_2, © Springer-Verlag London 2012 Most hairs viewed on trichoscopy are normal terminal hairs that are more than 55 m m wide and are uniform in thickness and color [ 1, 2 ] . Hair shaft thickness may be roughly estimated with a handheld dermoscope (thin, normal, thick). Many videodermoscopes include software allowing a...
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A technique for genetic modification of hair follicles was developed which results in efficient alteration of the hair shaft phenotype. High-level in vivo transgene expression was maintained in hair follicles such that growing hair shafts were phenotypically altered. Mouse anagen skin fragments, maintained in histoculture, were genetically modified at high efficiency with adenoviral-GFP. The hi...
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DNA isolation from hair shafts can involve a number of steps, each of which adds time to the procedure and increases the risk of contamination. A simple alkaline digestion procedure that directly dissolves hairs was developed and compared with a widely used glass grinding/organic extraction method, using samples collected from 30 volunteers with varying population ancestries, hair colors, and h...
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ژورنال
عنوان ژورنال: Genes
سال: 2018
ISSN: 2073-4425
DOI: 10.3390/genes9120640